Delayed Onset of Malignant Hyperthermia: A Case Report.
10.4266/kjccm.2009.24.3.168
- Author:
Jeong Wook LIM
1
;
Seok Kon YEO
;
Seong Hwan YANG
;
In Seok HWANG
;
Jong Soo LEE
Author Information
1. Department of Neurosurgery, Daejeon Sun General Hospital, Daejeon, Korea. magicdoctor@hanmail.net
- Publication Type:Case Report
- Keywords:
delayed malignant hyperthermia;
ryanodine receptor;
sevoflurane
- MeSH:
Adult;
Anesthesia;
Decompressive Craniectomy;
Fever;
Hematoma, Subdural, Acute;
Humans;
Male;
Malignant Hyperthermia;
Methyl Ethers;
Muscle Rigidity;
Muscular Diseases;
Ryanodine Receptor Calcium Release Channel
- From:The Korean Journal of Critical Care Medicine
2009;24(3):168-171
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant hyperthermia is a potentially fatal genetic and metabolic myopathy that presents with high fever, and muscle rigidity, and it often occurs after administering anesthetic medication. Most cases of malignant hyperthermia occur during anesthesia or surgery, but delayed malignant hyperthermia is very rare, and if it is detected late, it has a high mortality rate. A 39-year-old male with an acute subdural hematoma underwent decompressive craniectomy without any intraoperative medical problems, but a high fever above 40degrees C occurred after 8 hours and he was dead in spite of aggressive management after 48 hours postoperatively. We present here a case of delayed malignant hyperthermia along with a review of the related literature.
