Primary Small Cell Carcinoma of the Parotid Gland.
- Author:
Hyung Wook CHANG
1
;
Hyun Woo DO
;
Dong Won SHIN
;
Woo Seok KIM
Author Information
1. Department of Otolaryngology, College of Medicine, Catholic University of Daegu, Daegu, Korea. hwchang@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Parotid gland;
Neuroendocrine;
Small cell
- MeSH:
Carcinoma, Neuroendocrine;
Carcinoma, Small Cell*;
Head;
Humans;
Larynx;
Lung;
Mitosis;
Neck;
Neoplasm Metastasis;
Parotid Gland*;
Phosphopyruvate Hydratase;
Prognosis;
Salivary Glands
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2004;47(3):282-285
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Small cell neuroendocrine carcinomas mainly occur in the lung. Four percent of small cell carcinomas arise in extrapulmonary sites. In the head and neck region, small cell carcinomas arise most commonly in the larynx and very rarely in the parotid gland. Although the prognosis for patients with small cell carcinoma of the salivary glands is better than for those with small cell carcinoma of the lung or larynx, it is a high grade malignancy that is treated aggressively. We have recently experienced a case of primary small cell neuroendocrine carcinoma of parotid gland with extensive neck metastases. The histopathologic findings showed undifferentiated small cells with hyperchromatic nuclei, numerous mitoses, ductal differentiations and squamous changes. The positive findings for CD56 and neuron specific enolase staining determined this carcinoma to be a neuroendocrine subtype, and the patient received chemoradiation after surgery. We present this case with a review of literatures.
