Status of Hepatitis C in Hansen's Disease.
- Author:
Jong Pill KIM
1
;
Rae Hwan LEE
Author Information
1. Institute of Leprosy Research, Korean Hansen Welfare Association, Korea. dr_jpkim@hotmail.com
- Publication Type:Original Article
- Keywords:
Hansen's disease;
Hepatitis C Virus
- MeSH:
Genotype;
Hepacivirus;
Hepatitis;
Hepatitis C;
Humans;
Leprosy;
Polymerase Chain Reaction;
Prevalence
- From:Korean Leprosy Bulletin
2009;42(1):55-66
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
According to the reports, the prevalence of anti-HCV is about 1%. In past, the results of the high prevalence of anti-HCV in the patients of Hansen's disease were reported. So we study about the status of Hepatitis C of persons affected Hansen's disease. 1. The prevalence of anti-HCV is 35.1%(persons affected Hansen's disease), 0%(health contact), 0.71%(control, general populations). 2. Positivity of RT PCR is 88% in HCV-Ab-positive persons affected Hansen's disease. In the genotype of hepatitis C, type 1 genotype is 68%, and type 2 is 32%. 3. Statistical signification between patients & non-patients in ALT and HCV-Ab-positivity is found P=0.02, P=0.00) and statistical signification according to result of Hepatitis C antibody in ALT, GTT, and AFP is found in persons affected Hansen's disease(P=0.015, P=0.036, P=0.017).
