Cytology of Nasal Secretions in Rhinitis and Sinusitis.
- Author:
Ji Won KANG
1
;
Seung Heon SHIN
;
Kwang Hoon KIM
;
Jin Ho SOHN
;
Sang Gyung KIM
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Taegu Hyosung, Taegu, Korea. Catho97@nownuri.nowcom.co.kr
- Publication Type:Original Article
- Keywords:
Nasal secretion;
Cytology;
Inflammatory cell
- MeSH:
Cell Count;
Dithiothreitol;
Eosinophils;
Humans;
Lymphocytes;
Mucous Membrane;
Neutrophils;
Nose Diseases;
Paranasal Sinuses;
Rhinitis*;
Sinusitis*
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
1998;41(5):586-589
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Inflammatory cells in nasal secretions could reflect pathologic conditions occurring in the mucosa of the nasal and paranasal sinuses. But the cytologic investigation of the nasal secretions has not been fully accepted as a clinical examination. The aim of this study was to evaluate the quantitive cytologic study of various nasal diseases and the clinical value of cytologic examination of nasal secretions. MATERIALS AND METHODS: We studied 8 patients with chronic sinusitis, 8 patients with nasal polyposis, 23 patients with allergic rhinitis, and 11 patients with hypertrophic rhinitis. The nasal secretions were treated with dithiothreitol and examined at a magnification of 400X under a light microscope. The differential cell count and frequency of appearance of individual cell type was evaluated. RESULTS: The majority of inflammatory cells were eosinophil in allergic rhinitis and hypertrophic rhinitis. In chronic sinusitis and nasal polyposis, the majority were neutrophil. Eosinophils and lymphocytes appear very frequently in nasal polyposis. CONCLUSION: The result suggests that the cytologic study of nasal secretion is a simple and useful method to determine cell populations under various conditions.
