A Case of Mantle Cell Lymphoma with Skin Metastasis.
- Author:
Hye Young JU
1
;
Hye Seung KIM
;
Jun Young LEE
;
Hyung Ok KIM
;
Young Min PARK
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. yymmpark6301@hotmail.com
- Publication Type:Case Report
- Keywords:
Mantle cell lymphoma;
Nodule;
Skin
- MeSH:
Abdomen;
B-Lymphocytes;
Bone Marrow;
Cyclin D;
Dermis;
Drug Therapy, Combination;
Gastrointestinal Tract;
Humans;
Lymphatic Diseases;
Lymphocytes;
Lymphoma;
Lymphoma, Mantle-Cell;
Male;
Middle Aged;
Neoplasm Metastasis;
Skin;
Spleen
- From:Korean Journal of Dermatology
2010;48(2):158-160
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mantle cell lymphoma is a malignant lymphoma derived from a subset of B-cells that are localized in the mantle area of the lymphoid follicle. Extranodal involvement is frequent, and especially in the bone marrow, spleen, gastrointestinal tract and Waldeyer's ring, but skin is rarely affected. A 47-year-old male presented with a 40 day history a nodule on the abdomen on the abdomen. The histopathologic examination showed numerous atypical, small to medium sized lymphoid cells in the entire dermis. Immunohistochemically, the tumor cells were positive for CD20, CD5, CD79a and cyclin D. Our patient showed complete disappearance of his skin lesions and lymphadenopathy after combination chemotherapy.
