Vitamin B6 Requirement: Indicators and Factors Affecting.
10.4163/kjn.2010.43.3.315
- Author:
Youn Ok CHO
1
Author Information
1. Department of Food and Nutrition, Ducksung Women's University, Seoul 132-714, Korea. yunokcho@duksung.ac.kr
- Publication Type:Review
- Keywords:
vitamin B6 requirement;
vitamin B6 status;
vitamin B6 indicator;
vitamin B6 DRI
- MeSH:
Alanine Transaminase;
Amino Acids;
Aspartate Aminotransferases;
Biological Availability;
Chronic Disease;
Erythrocytes;
Glucose;
Humans;
Neurotransmitter Agents;
Plasma;
Pyridoxal;
Pyridoxic Acid;
Vitamin B 6;
Vitamins
- From:The Korean Journal of Nutrition
2010;43(3):315-323
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to establish the selection of indicators for estimating and factors affecting the requirement of vitamin B6. There has been a need to establish the human requirements of vitamin B6 since vitamin B6 is thought to be involved in more than one hundred biochemical reactions as a coenzyme in the metabolism of amino acids, glucose, and lipid, and the synthesis of neurotransmitters. For the review of the literature, this study included from early findings of the sixties to studies of 2009. This study suggests that plasma pyridoxal 5' phosphate (PLP) is the best single indicator of vitamin B6 status for the healthy but not for the non-healthy. Erythrocyte aspartate aminotransferase and alanine aminotransferase activation by PLP as an indirect measure and urinary 4-pyridoxic acid excretion as a direct measure are useful as supporting indicators. Bioavailability, nutrient interaction, physiological need, and chronic diseases may increase the requirement for vitamin B6. However, these effects can not be quantified due to insufficient evidences.
