A Case of Oncocytic Carcinoma Arising in the Submandibular Gland.
10.3342/kjorl-hns.2012.55.3.173
- Author:
Seung Kuk SHIN
1
;
Young Ok LEE
;
Byung Joo LEE
;
Yun Sung LIM
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine, Busan, Korea. splash1@hanmail.net
- Publication Type:Case Report
- Keywords:
Submandibular gland neoplasms;
Lymphatic metastasis
- MeSH:
Adenoma;
Biopsy;
Biopsy, Fine-Needle;
Carcinoma, Mucoepidermoid;
Diagnosis, Differential;
Fractures, Bone;
Head;
Humans;
Lung;
Lymphatic Metastasis;
Male;
Neck;
Neck Dissection;
Neoplasm Metastasis;
Salivary Glands;
Submandibular Gland;
Submandibular Gland Neoplasms
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2012;55(3):173-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Oncocytic neoplasm of the head and neck region accounts for approximately 1% of all salivary gland tumors, but only 5% of oncocytic neoplasm is malignant. Oncocytic carcinoma arising in the submandibular gland is exceedingly rare. We encountered a sixty seven-year-old male patient who presented with multiple mass in the right neck. Fine needle aspiration biopsy revealed a salivary gland tumor of predominantly oncocytic form, and a differential diagnosis included oncocytic adenoma or mucoepidermoid carcinoma. A right submandibular gland resection and modified radical neck dissection were performed. Histologically, the tumor cells showed nuclear pleomorphism, and stromal invasion, which were compatible with oncocytic carcinoma. After surgery, the entire neck region was irradiated. Seventeen months after the initial surgery, multiple metastases to the bone and lung were detected from the incidental pathologic bone fracture of the right humerus; palliative chemotherapy was performed to resolve this. We report a case of oncocytic carcinoma in the submandibular gland with a review of literature.
