A Case of Malignant Peripheral Nerve Sheath Tumor in Parapharyngeal Space.
10.3342/kjorl-hns.2012.55.3.181
- Author:
Hyun Sub LEE
1
;
Chang Hee LEE
;
Sung Min JIN
;
Sang Hyuk LEE
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. entlsh@hanmail.net
- Publication Type:Case Report
- Keywords:
Malignant peripheral nerve sheath tumor;
Parapharynx;
Neurofibrosarcoma;
Malignant schwannoma;
Malignant neurilemmoma
- MeSH:
Deglutition Disorders;
Extremities;
Head;
Headache;
Human Body;
Humans;
Incidence;
Middle Aged;
Neck;
Neurilemmoma;
Neurofibromatosis 1;
Neurofibrosarcoma;
Peripheral Nerves;
Recurrence;
Sarcoma
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2012;55(3):181-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The malignant peripheral nerve sheath tumor is an extremely rare soft tissue sarcoma. It is a highly malignant sarcoma, which is locally invasive, frequently leading to multiple recurrences and eventual metastatic spread. The peak incidence of disease is known to occur sporadically between the age of 20s and 50s, and is usually associated with the neurofibromatosis type I. In human body, the trunk and extremities are the most commonly involved sites, with only 8-14% of all lesions appearing in the head and neck region. We present a case of malignant peripheral nerve sheath tumor involving the right parapharynx in a 48-year-old patient who complained of headaches in the right parietal area and of dysphagia that aggravated over a month. After surgery, tumor was finally diagnosed as malignant peripheral nerve sheath tumor by histopathologic examinations. The authors report a case of malignant peripheral nerve sheath tumor in the right parapharynx with a review of the literature.
