Generalized Tonic-Clonic Seizure following Myelography with Iohexol (Omnipaque.): A Case Report.
10.4055/jkoa.2004.39.5.586
- Author:
Kyung Jin SONG
1
;
Kwang Bok LEE
Author Information
1. Department of Orthopedic Surgery, College of Medicine, Institute for Medical Science, Chonbuk National University Hospital, Jeonju, Korea. osdr2815@chol.com
- Publication Type:Case Report ; Clinical Trial
- Keywords:
Myelogram;
Seizure;
Iohexol
- MeSH:
Emergency Treatment;
Headache;
Humans;
Iohexol*;
Myelography*;
Psychotic Disorders;
Seizures*;
Vomiting
- From:The Journal of the Korean Orthopaedic Association
2004;39(5):586-588
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We encountered a patient who had a rare occurrence of a seizure after lumbar myelography from the beginning of this untoward side effect. Clinical trials with iohexol in myelography have demonstrated a good tolerability of this water-soluble contrast medium. However, there have been a few reports that have shown acute adverse reactions such as headaches, vomiting, psychosis, confusion and generalized tonic-clonic seizures. Despite the reports on the safety of iohexol use, it may cause a generalized seizure attack without an epileptogenic history. Therefore, thorough attention and the preparation for emergency treatments for the seizure are essential in every myelography using iohexol as a contrast medium. Moreover, in order to avoid unwanted legal problems, the patients and their family need to be informed of the necessity and possible side effects associated with myelography.
