Application of Helical Tomotherapy for Two Cases of Advanced Hepatocellular Carcinoma.
10.3904/kjim.2011.26.2.201
- Author:
Joon Sung KIM
1
;
Chan Ran YOU
;
Jeong Won JANG
;
Si Hyun BAE
;
Jong Yong CHOI
;
Seung Kew YOON
;
Chul Seung KAY
Author Information
1. Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. baesh@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma, hepatocellular;
Venous thrombosis;
Metastasis;
Radiotherapy
- MeSH:
Adult;
Carcinoma, Hepatocellular/radiography/*radiotherapy/secondary;
Chemotherapy, Adjuvant;
Dose Fractionation;
Female;
Humans;
Imaging, Three-Dimensional;
Liver Neoplasms/pathology/radiography/*radiotherapy;
Male;
Neoplasm Invasiveness;
Radiographic Image Interpretation, Computer-Assisted;
*Radiotherapy Planning, Computer-Assisted;
*Radiotherapy, Conformal;
*Tomography, Spiral Computed;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2011;26(2):201-206
- CountryRepublic of Korea
- Language:English
-
Abstract:
The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure to the rest of the liver and adjacent organs. Recently, the concept of "adaptive radiotherapy," such as with helical tomotherapy, has been introduced for treating HCC. Helical tomotherapy obtains an image from the computed tomography component, which allows targeted regions to be visualized prior to, during, and immediately after each treatment and delivers intensity-modulated radiation therapy. We report two patients with advanced HCC who underwent tomotherapy treatment. One was a patient afflicted with advanced HCC and a portal vein tumor thrombus, which was treated with tomotherapy combined with transarterial chemolipiodolization. The other was a patient afflicted with multiple pulmonary metastases treated with tomotherapy followed by systemic chemotherapy.
