A Case of Allergic Fungal Sinusitis.
- Author:
Ki Sang RHA
1
;
Gwang Cheol SIN
;
O Young LEE
;
Jin Man KIM
Author Information
1. Department of Otolaryngology, College of Medicine, Chungnam National University, Taejon, Korea.
- Publication Type:Case Report
- Keywords:
Allergic fungal sinusitis;
Sinusitis;
Endoscopic sinus surgery
- MeSH:
Antigens, Fungal;
Diagnosis;
Eosinophilia;
Eosinophils;
Humans;
Hypersensitivity, Immediate;
Hyphae;
Immunoglobulin E;
Korea;
Mucins;
Mucus;
Nasal Polyps;
Sinusitis*;
Skin;
Tomography, X-Ray Computed
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2000;43(4):438-441
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since the initial description of allergic fungal sinusitis by Millar et al. in 1981, reported cases have been increasing. However, one case of allergic fungal sinusitis has been reported in Korea. The diagnosis can be established by demonstrating type I hypersensitivity reaction, nasal polyposis, characteristic CT scan, eosinophilic mucus without evidence of fungal invasion into sinus tissue, and a positive fungal stain or culture of sinus contents. The authors present a case which met the diagnostic criteria of allergic fungal sinusitis. This patient had nasal polyp and showed elevated level of total IgE, peripheral eosinophilia, positive MAST and strongly positive immediate skin reactivity to fungal antigens. On histologic examination, typical allergic mucin containing sheets of eosinophils, Charcot-Leyden crystals was found. Fungal hyphae were also found in the mucin content.