Intravitreal Triamcinolone Injection for Uveitic Cystoid Macular Edema.
- Author:
Hun YANG
1
;
Jong Hyup HYUN
;
Sung Chul LEE
Author Information
1. The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. sunglee@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Cystoid macular edema;
Foveal retinal thickness;
Triamcinolone acetonide;
Uveitis
- MeSH:
Cataract;
Filtering Surgery;
Follow-Up Studies;
Humans;
Inflammation;
Intraocular Pressure;
Intravitreal Injections;
Macular Edema*;
Recurrence;
Retinaldehyde;
Retrospective Studies;
Triamcinolone Acetonide;
Triamcinolone*;
Uveitis;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2004;45(9):1487-1495
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the results of intravitreal injection of triamcinolone acetonide (TA) for the treatment of chronic uveitic cystoid macular edema (CME). METHODS: Six patients, 8 eyes with refractory uveitic CME were included in the study. Four milligrams of TA was injected into the vitreous cavity. The clinical outcome and complication were reviewed, retrospectively. RESULTS: Ten intravitreal injections of TA were performed, and the mean follow-up duration was 10.4 months (6~19 months). Foveal retinal thickness diminished and CME improved anatomically in 7 (88%) eyes. Visual acuity improved by 1.75 lines of the Snellen chart in 6 (75%) eyes, and the time to improvement varied from 1 week to 8 months. Inflammation decreased in all eyes and there was symptomatic improvement in 6 (75%) eyes. CME recurred in 3 (38%) eyes at 4 to 16 weeks and re-treatments were performed in 2 eyes. Intraocular pressure increased in 3 eyes and one eye needed additional filtration surgery. Cataract worsened in one eye. CONCLUSIONS: Intravitreal triamcinolone injection effectively induced anatomic and symptomatic resolution, and decreased inflammation in uveitic CME patients. Nevertheless, the visual improvement was modest, and consideration for recurrence and complication is necessary.
