Epstein Barr Virus-Associated Angiocentric T Cell Lymphoma in Nasal Cavity of Renal Transplantation Recipient.
- Author:
Hyun Wook KANG
1
;
Ji Eun LEE
;
June Sik PARK
;
Sang Sook LEE
Author Information
1. Department of Otorhinolaryngology, College of Medicine, Kyungpook National University, Kyungpook, Korea. junesik@kyungpook.ac.kr
- Publication Type:Case Report
- Keywords:
PTLD(Posttransplant lymphoproliferative disorder);
Angiocentric T cell lymphoma;
Epstein barr virus
- MeSH:
Adult;
Female;
Herpesvirus 4, Human;
Humans;
In Situ Hybridization;
Kidney Transplantation*;
Lymphoma, T-Cell*;
Lymphoproliferative Disorders;
Nasal Cavity*;
Organ Transplantation;
Prognosis;
Radiotherapy;
RNA, Messenger;
Siblings;
Transplants
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
1999;42(8):1041-1045
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posttransplant lymphoproliferative disorder (PTLD)is recognized as a significant and morbid complication of organ transplantation. The majority of PTLD is of B cell origin and strongly associated with Epstein Barr virus (EBV). T cell origin is uncommon and has a poor prognosis. There are only a few cases of PTLD of T cell origin, associated with EBV. We have experienced a case of angiocentric T cell lymphoma in nasal cavity, associated with EBV in a renal transplanted recipient. The patient was 25 years old woman who received transplant from her brother in 1995. Angiocentric T cell lymphoma was developed 33 months after the transplantation. We detected EBV mRNA in the neoplastic cells by in situ hybridization. She was treated by radiotherapy and is in complete remission state at present.
