The Value of Cardiovascular Risk Factors in Predicting Hearing Recovery of Sudden Sensorineural Hearing Loss.
10.3342/kjorl-hns.2016.59.7.495
- Author:
Yong Jun CHOI
1
;
Sung Ho GONG
;
Se In CHOI
;
Gun Hee YU
;
Yun Sung LIM
;
Seok Won PARK
;
Chang Gun CHO
;
Joo Hyun PARK
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Dongguk University, Ilsan Hospital, Goyang, Korea. parkzzu19@dongguk.ac.kr
- Publication Type:Original Article
- Keywords:
Cardiovascular risk factor;
Steroid;
Sudden sensorineural hearing loss
- MeSH:
Blood Pressure;
Body Mass Index;
Cholesterol;
Diabetes Mellitus;
Follow-Up Studies;
Hearing Loss, Sensorineural*;
Hearing*;
Humans;
Methods;
Retrospective Studies;
Risk Factors*;
Smoke;
Smoking;
Treatment Outcome
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2016;59(7):495-501
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Several prognostic factors are known to be related to the recovery of sudden sensorineural hearing loss (SSNHL). Recent studies have suggested that cardiovascular risk factors (CVRFs) are associated with the occurrence of SSNHL. However, the value of CVRFs as a predictor of recovery in patients with SSNHL has been rarely evaluated. We aim to evaluate the prognostic value of CVRFs in relation to hearing recovery of SSNHL. SUBJECTS AND METHOD: A total of 278 patients who were diagnosed and treated for SSNHL and who underwent blood sampling and follow-ups for more than 3 months were reviewed retrospectively. We reviewed CVRFs such as age, body mass index, blood pressure, cholesterol, smoking history, the presence of diabetes mellitus and other related underlying diseases. Patients were divided into three groups (low, medium, and high CVRF groups) according to the CVRF grades. Hearing thresholds were repeatedly measured on the initial visit, 1 week, 1 month and 3 months after treatment. Treatment outcome was analyzed by comparing hearing recovery rate and post-treatment audiometric changes among the three CVRF groups. RESULTS: Seventy (25.2%), 129 (46.4%) and 79 (28.4%) patients were included into the low, medium and high CVRF groups, respectively. The hearing threshold was significantly reduced at 3 months after treatment in all three groups (p<0.001). The hearing recovery rate of the low CVRF group was significantly higher than that of the medium and high CVRF group (p=0.011). On the last visit, the high CVRF group significantly showed more poor hearing improvement than the low CVRF group did (p=0.045). CONCLUSION: Our findings suggest that the presence of CVRFs may be a poor prognostic sign for hearing recovery in patients with SSNHL.
