Characterization of Membrane Excitability of Purkinje Cells in Vestibulocerebellum Using Patch Clamp Techniques.
10.3342/kjorl-hns.2013.56.4.185
- Author:
Chang Hee KIM
1
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. ryomachang@naver.com
- Publication Type:Review
- Keywords:
Electrophysiology;
Patch clamp;
Purkinje cell;
Vestibulocerebellum
- MeSH:
Cerebellar Cortex;
Cerebellar Nuclei;
Cerebellum;
Electrophysiology;
Learning;
Membranes;
Memory;
Neurons;
Patch-Clamp Techniques;
Purkinje Cells;
Vestibular Nuclei
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2013;56(4):185-190
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cerebellum is known as a center for sensory/motor coordination and memory storage in motor learning. The vestibular nuclei have extensive afferent and efferent connections with posterior cerebellum which can be referred to as vestibulocerebellum. While secondary vestibular afferents are distributed bilaterally in the vestibulocerebellum, primary afferents may directly project to ipsilateral vestibulocerebellum. The Purkinje cells which are the only output neurons from the cerebellar cortex receive vestibular information via parallel and climbing fibers. That information is integrated and encoded in the Purkinje cells and then conveyed into the vestibular nucleus or deep cerebellar nucleus, which permits adaptive guidance of vestibular function by the vestibulocerebellum.
