Biologic Changes of Xenograft ( LUBBOC ) in the Surgical Treatment of Calcaneal Fractures.
- Author:
Ki Soo KIM
1
;
Young Soo CHOI
;
Kyung Sung YOUM
;
Kyung Jin JOE
;
Kyeong Soo KIM
Author Information
1. Department of Orthopedic Surgery, Kwang ju Christian Hospital.
- Publication Type:Original Article
- Keywords:
Calcaneal fractures;
Xenograft
- MeSH:
Biopsy;
Bone Substitutes;
Calcaneus;
Heterografts*;
Magnetic Resonance Imaging;
Osteoblasts;
Osteoclasts
- From:The Journal of the Korean Orthopaedic Association
1999;34(4):699-705
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the biologic changes of xenograft (Lubboc, Transphyto S. A., Clermont-Ferrand, France) applied in the surgical treatment of calcaneal fractures. MATERIALS AND METHODS: Xenograft were used in twenty-five calcaneal fractures, as bone substitutes for mechanical support of the articular surface from March 1994 to December 1996. Twenty-four cases had obtained clinical and radiological bony union without complications. We performed biopsy at the xenograft area in eight cases when the hardware was removed. And then we took a magnetic resonance imaging of the calcaneus after the biopsy in three cases. RESULTS: The pathologic findings of the xenografts showed dead bony trabeculae with inflammed fibrous tissue. There was no osteoblastic activity but some osteoclastic activity was seen in the graft-host junctional area. MRI findings showed that there was well-circumscribed, low-signal intensity in the xenograft area contrast to the normal bony signal intensity. Its lesion was equal to the sclerotic finding in the calcaneal radiograph. CONCLUSIONS: Xenograft (LUBBOC'), which is used in the mechanical support of the articular surface, apparently lacks osteogenic capacity.
