Korean Shock Society septic shock registry: a preliminary report.
- Author:
Tae Gun SHIN
1
;
Sung Yeon HWANG
;
Gu Hyun KANG
;
Won Young KIM
;
Seung Mok RYOO
;
Kyuseok KIM
;
You Hwan JO
;
Sung Phil CHUNG
;
Young Seon JOO
;
Jin Ho BEOM
;
Sung Hyuk CHOI
;
Young Hoon YOON
;
Woon Yong KWON
;
Tae Ho LIM
;
Kap Su HAN
;
Han Sung CHOI
;
Gil Joon SUH
Author Information
- Publication Type:Multicenter Study ; Original Article
- Keywords: Sepsis; Septic shock; Mortality; Patient care bundles
- MeSH: Central Venous Pressure; Compliance; Emergency Service, Hospital; Humans; Hyperlactatemia; Hypotension; Lactic Acid; Male; Mortality; Oxygen; Patient Care Bundles; Prospective Studies; Resuscitation; Sepsis; Shock*; Shock, Septic*
- From: Clinical and Experimental Emergency Medicine 2017;4(3):146-153
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To evaluate the clinical characteristics, therapeutic interventions, and outcomes of patients with septic shock admitted to the emergency department (ED). METHODS: This study was a preliminary, descriptive analysis of a prospective, multi-center, observational registry of the EDs of 10 hospitals participating in the Korean Shock Society. Patients aged 19 years or older who had a suspected or confirmed infection and evidence of refractory hypotension or hypoperfusion were included. RESULTS: A total of 468 patients were enrolled (median age, 71.3 years; male, 55.1%; refractory hypotension, 82.9%; hyperlactatemia without hypotension, 17.1%). Respiratory infection was the most common source of infection (31.0%). The median Sepsis-related Organ Failure Assessment score was 7.5. The sepsis bundle compliance was 91.2% for lactate measurement, 70.3% for blood culture, 68.4% for antibiotic administration, 80.3% for fluid resuscitation, 97.8% for vasopressor application, 68.0% for central venous pressure measurement, 22.0% for central venous oxygen saturation measurement, and 59.2% for repeated lactate measurement. Among patients who underwent interventions for source control (n=117, 25.1%), 43 (36.8%) received interventions within 12 hours of ED arrival. The in-hospital, 28-day, and 90-day mortality rates were 22.9%, 21.8%, and 27.1%, respectively. The median ED and hospital lengths of stay were 6.8 hours and 12 days, respectively. CONCLUSION: This preliminary report revealed a mortality of over 20% in patients with septic shock, which suggests that there are areas for improvement in terms of the quality of initial resuscitation and outcomes of septic shock patients in the ED.
