A Case of Macroglossia due to Amyloidosis Associated with Multiple Myeloma.
10.3342/kjorl-hns.2013.56.1.37
- Author:
Rok Young KIM
1
;
John Jae Woon LEE
;
Dong Hoon LEE
;
Joon Kyoo LEE
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School, Hwasun Hospital, Hwasun, Korea. joonkyoo@jnu.ac.kr
- Publication Type:Case Report
- Keywords:
Amyloidosis;
Macroglossia;
Multiple Myeloma
- MeSH:
Airway Obstruction;
Amyloid;
Amyloidosis;
Dyspnea;
Female;
Humans;
Light;
Macroglossia;
Multiple Myeloma;
Plaque, Amyloid;
Plasmacytoma;
Proteins;
Serum Amyloid A Protein;
Stress, Psychological;
Tongue
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2013;56(1):37-40
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amyloidosis is a condition of abnormal deposition of extracellular insoluble fibrillar proteins, termed amyloid, in tissue and organs throughout the body. Systemic amyloidosis, consisting of light amyloid protein (AL protein), the spectrum of multiple myeloma and plasmacytoma, is categorized as a primary amyloidosis; secondary amyloidosis consists of an acute phase reactant serum amyloid A protein (AA protein), which is associated with neoplasm. Amyloid involvement of the tongue is almost always secondary to systemic AL amyloidosis. Macroglossia due to amyloid depositions can lead to serious airway obstruction. We report a case of a 68-year-old woman suffering from dyspnea due to macroglossia. She was diagnosed with amyloidosis associated with multiple myeloma.
