Prevention of New Vertebral Fractures after Treatment with Risedronate, Alendronate or Calcium Carbonate in Patients with Osteoporotic Compression Fracture Treated with Cement Augmentation.
10.4055/jkoa.2009.44.4.436
- Author:
Jin Young KIM
1
;
Eun Su MOON
;
Hwan Mo LEE
;
Seong Hwan MOON
;
Jin Oh PARK
;
Jee Ho HYUNG
;
Hak Sun KIM
Author Information
1. Department of Orthopaedic Surgery, College of Medicine, Yonsei University, Seoul, Korea. haksunkim@yuhs.ac
- Publication Type:Original Article
- Keywords:
Osteoporosis;
Compression fracture;
Risedronate;
Alendronate;
Calcium carbonate
- MeSH:
Alendronate;
Calcium;
Calcium Carbonate;
Etidronic Acid;
Follow-Up Studies;
Fractures, Compression;
Humans;
Kyphoplasty;
Osteoporosis;
Spine;
Vertebroplasty;
Risedronate Sodium
- From:The Journal of the Korean Orthopaedic Association
2009;44(4):436-441
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the rate of new fractures of the spine after risedronate, alendronate or calcium carbonate in patients who had vertebroplasty or kyphoplasty due to compression fracture. MATERIALS AND METHODS: We studied 292 patients with osteoporotic compression fractures who had received vertebroplasty or kyophoplasty between June 2003 and October 2007. Of these, 199 were evaluated for new fractures of the spine after treatment with risedronate, alendronate or calcium carbonate. Patients (n=199) were assigned to 1 of 4 groups: No treatment (n=71), risendronate (n=64), alendronate (n=42) or calcium carbonate group (n=22). RESULTS: New fractures of the spine were morphogenically found in 19 patients (26.8%) in the no treatment group, in 11 (17.2%) in the risendronate group, in 8 (19.1%) in the alendronate group, in 5 (22.8%) in the calcium carbonate group. Symptomatically, they were found in 6 patients (8.5%) in the no treatment group, in 4 (6.3%) in the risendronate group, in 3 patients (7.1%) in the alendronate group, and in 2 patients (9.1%) in the calcium carbonate group. CONCLUSION: At one year follow up none of the differences between groups in new fracture rates of the spine were statistically significant.
