The impact of magnesium sulfate as adjuvant to intrathecal bupivacaine on intra-operative surgeon satisfaction and postoperative analgesia during laparoscopic gynecological surgery: randomized clinical study.
10.3344/kjp.2017.30.3.207
- Author:
Khaled Salah MOHAMED
1
;
Sayed Kaoud ABD-ELSHAFY
;
Ali Mahmoud EL SAMAN
Author Information
1. Department of Anesthesia, College of Medicine, Assiut University, Assiut, Egypt. sayed_k_72@yahoo.com
- Publication Type:Controlled Clinical Trial ; Randomized Controlled Trial ; Original Article
- Keywords:
Bupivacaine;
Laparoscopic surgery;
Magnesium;
Postoperative pain;
Satisfaction;
Surgeon
- MeSH:
Analgesia*;
Anesthesia, Spinal;
Bupivacaine*;
Clinical Study*;
Female;
Gynecologic Surgical Procedures*;
Humans;
Incidence;
Intraoperative Period;
Laparoscopy;
Magnesium Sulfate*;
Magnesium*;
Pain Measurement;
Pain, Postoperative;
Postoperative Nausea and Vomiting;
Prospective Studies;
Pruritus;
Shoulder Pain;
Urinary Retention;
Visual Analog Scale
- From:The Korean Journal of Pain
2017;30(3):207-213
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Surgeon satisfaction and patient analgesia during the procedure of laparoscopic surgery are important issues. The aim of this work was to study if an intrathecal (IT) Bupivacaine combined with Magnesium sulfate may or may not provide good surgeon satisfaction in addition to improvement of intraoperative and postoperative analgesia. METHODS: Sixty female patients were enrolled in this prospective, randomized, double-blind controlled clinical trial study. All patients were operated for gynecological laparoscopic surgery under spinal anesthesia. Patients were divided into two groups (Bupivacaine and Magnesium). Group Bupivacaine (30 patients) received intrathecal Bupivacaine 0.5% only (15 mg), while 30 patients in group Magnesium received intrathecal Bupivacaine (15 mg) in addition to intrathecal Magnesium sulfate (50 mg). The sensory block level, the intensity of motor block, the surgeon satisfaction, the intraoperative visual analog scale (VAS) for pain assessment, the postoperative VAS, and side effects were recorded during the intraoperative period and within the first 24 hours after surgery in the post-anesthesia care unit. RESULTS: Surgeon satisfaction, intraoperative shoulder pain, postoperative pain after 2 h, and perioperative analgesic consumption (ketorolac) were significant better in group Magnesium than in group Bupivacaine. (P < 0.05). The onset of motor and sensory blocks was significant longer in group Magnesium than the other one. The incidence of PONV, pruritus and urinary retention was insignificant statistically between both groups. CONCLUSIONS: Magnesium sulfate if used intrathecally as an adjuvant to Bupivacaine would provide a better surgeon satisfaction and would improve the analgesic effect of spinal anesthesia used for gynecological laparoscopic surgery.
