Relationship between seroprevanlence of Helicobacter pylori infection and childhood breastfeeding duration
- Author:
Bang Van Nguyen
- Publication Type:Journal Article
- Keywords:
breastfeeding duration;
children;
helicobacter pylori;
seroprevalence
- MeSH:
Helicobacter pylori/ pathogenicity;
Child
- From:Journal of Medical Research
2007;55(6):154-158
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Helicobacter pylori (HP), the main reason caused digestive disease in many people. Objectives: To explore the relationship between seroprevalence of HP in children and the duration of breastfeeding (BF) in childhood. Subjects and method:Data on BF duration were collected, using a structured questionnaires, then analyzed by logistic regression, in three different groups: (1) 764 children aged from 6 months to 15 years admitted to or visiting a tertiary teaching hospital, (2) 369 children under 18 from a rural village in the centre and (3) 408 children under 18 from a multi - ethnic village in the mountainous area of the northern part of Vietnam. HP infection was determined by ELISA technique. Results: HP seroprevalence was of 26.0% (69/265) in children breastfed longer than 6 months, significant lower than 37.4% (308/556) in children breastfed shorter than 6 months in the first group [p<0.02, OR (95% CI): 0.63 (0.41 - 0.84)]. This rate was of 39.7% (27/68) in children breastfed longer than 24 months, significant lower than 59.1 % (178/301) in children breastfed shorter than 24 months in the second group [p=0.01, OR (95% CI): 0.46 (0.27 - 0.78)]. However, in the 3rd group of different minority ethnics from mountainous area, where living and hygiene levels were low, HP seroprevalence was of 29.7% (82/276), significant higher than 20.5% (27/132) in children breastfed shorter than 12 months [p = 0.03, OR (95% CI): 1.64 (1.00 - 2.70)]. Conclusion: Long duration of breastfeeding seemed protective against HP acquisition in Kinh children but might become a risk factor for HP infection in mountainous children.
