Prognostic Factors of Invasive Fungal Sinusitis.
- Author:
Myung Chul LEE
1
;
Jae Jin SONG
;
Han Sin JUNG
;
Seung Sin LEE
;
Chae Seo RHEE
;
Chul Hee LEE
;
Yang Gi MIN
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Korea. csrhee@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Mycosis;
Sinusitis;
Prognosis
- MeSH:
Causality;
Debridement;
Fibrinogen;
Humans;
Immunocompromised Host;
Prognosis;
Retrospective Studies;
Sinusitis*;
Survival Rate
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2003;46(10):841-845
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Fulminant invasive fungal sinusitis (IFS) is an aggressive, destructive disease most commonly affecting the immunocompromised hosts. This study aimed to investigate the clinical features of invasive fungal sinusitis and to determine its prognostic factors. MATERIALS AND METHOD: Fifteen cases of invasive fungal sinusitis were retrospectively reviewed. Prognosis was analyzed according to predisposing factors including the underlying disease, the extent of disease, the mycotic species, and treatment modalities. RESULTS: Overall 5-year survival rate of the patients with IFS was 60%. There was significant survival gain in the group for which underlying disease was well controlled (p=0.04). There was no difference in survival in terms of mycotic species and extent of disease at presentation. No statistically significant difference in survival was observed between the conservative surgery and the radical surgery group. CONCLUSION: Survival is usually determined at the very early period of treatment. The most important prognostic factor is not the surgical modalities including wide surgical resection or conservative debridement, but the optimal control of underlying disease.
