Investigation of Helicobacter Pylori Colonization in Tonsillectomy and Adenoidectomy Specimens using Campylobacter Like Organism Test.
- Author:
Kyu Sup CHO
1
;
Soo Geun WANG
;
Byung Joo LEE
;
Jin Chun LEE
;
Hyun Sun LEE
;
Eui Kyung GOH
Author Information
1. Department of Otolaryngology, College of Medicine, Pusan National University, Busan, Korea. wangsg@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Helicobacter pylori;
Tonsil;
Adenoid
- MeSH:
Adenoidectomy*;
Adenoids;
Anesthesia, General;
Campylobacter*;
Colon*;
Gastritis;
Helicobacter pylori*;
Helicobacter*;
Humans;
Lymphoid Tissue;
Lymphoma, B-Cell;
Palatine Tonsil;
Prevalence;
Risk Factors;
Stomach Diseases;
Tonsillectomy*;
Ulcer
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2003;46(10):846-850
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Helicobacter pylori infection is strongly associated with chronic gastritis and ulcer disease and is a risk factor for gastric carcinoma and primary gastric B-cell lymphoma. Palatine tonsils and adenoids are a component of mucosa-associated lymphoid tissue (MALT) and represent an extragastric reservoir for H. pylori infection. This study was designed to find out the settling frequency of H. pylori in tonsil and adenoid tissues by Compylobacter like organism (CLO) test on tonsillectomy and adenoidectomy specimens in Koreans. MATERIALS AND METHOD: We reviewed the records of 52 patients aged 3 to 51 who had undergone an adenoidectomy, tonsillectomy, or adenotonsillectomy procedure under local or general anesthesia. Two millimeter diameter tissue pieces had been obtained from each adenoid and tonsil specimens were placed in CLO test kit. Color changes were noted after 20 minutes and after periods of 1, 3, and 24 hours. RESULTS: Thirty three (63.5%) of the 52 patients were shown to be H. pylori positive. H. pylori positive rate was not significantly different according to operation methods, age and sex. H. pylori positive rate in tonsil specimens (62.7%) was significantly higher than that in adenoid specimens (17.6%)(p<0.05). CONCLUSION: This results suggest that palatine tonsils represent an extragastric reservoir for H. pylori infection. Tonsillectomy may be associated with decreased prevalence of H. pylori colonization. Further study is needed about correlation between H. pylori colonization in tonsil and H. pylori associated gastric disease.
