A Case of Immunoglobulin G4-Related Sialadenitis and Dacryoadenitis.
10.3342/kjorl-hns.2013.56.7.444
- Author:
Kyoung Kyu LEE
1
;
Hun Po CHO
;
Young Min LEE
;
Jun Ho PARK
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Daegu Fatima Hospital, Daegu, Korea. jhpark@fatima.or.kr
- Publication Type:Case Report
- Keywords:
Immunoglobulin G;
Mikulicz's disease;
Sialadenitis
- MeSH:
Dacryocystitis;
Humans;
Hypertrophy;
Immunoglobulin G;
Immunoglobulins;
Lacrimal Apparatus;
Salivary Gland Calculi;
Salivary Glands;
Sialadenitis;
Sjogren's Syndrome
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2013;56(7):444-447
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypertrophy of salivary gland was developed by sialadenitis, sialolithiasis, autoimmune diasease and other tumorous conditions. Mikulicz's disease has been used to describe symptomless hypertrophy of the salivary gland and lacrimal gland. In the past, it was thought that Mikulicz's disease is included within the diagnosis of Sjogren's syndrome. However, Mikulicz's disease represents Immunoglobulin G4 (IgG4)-related hypertrophy of salivary gland and lacrimal gland by an elevated level of IgG4 in the serum of the patient and good responsiveness to glucocorticoid, eventually leading to recovery of gland function. We have experienced a case of IgG4-related sialadenitis and dacryoadenitis with bilateral hypertrophy of parotid, submandibular and lacrimal glands. We report this case with a brief review of the literature.
