Short-term Prophylactic Antibiotics in Total Hip Arthroplasty.
10.4055/jkoa.2005.40.4.428
- Author:
Jae Suk CHANG
1
;
Yang Soo KIM
;
Hyun Chul SHON
;
Ji Wan KIM
;
Su Young CHUNG
;
Jai Hyung PARK
Author Information
1. Department of Orthopedic Surgery, Asan Medical Center, College of Medicine, Ulsan University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Total hip arthroplasty;
Infection;
Antibiotics
- MeSH:
Anti-Bacterial Agents*;
Arthroplasty, Replacement, Hip*;
Humans;
Retrospective Studies
- From:The Journal of the Korean Orthopaedic Association
2005;40(4):428-433
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to determine an adequate period of prophylactic antibiotics administration in order to prevent postoperative acute infection in total hip arthroplasty patients. MATERIALS AND METHODS: A retrospective analysis of the periods of antibiotics administration was performed in 467 cases. They were divided into three groups: those who received antibiotics more than hours postoperatively (group I), up to 48 hours postoperatively (group II), and those received antibiotics only on the day of the surgery (group III). The antibiotics used was first generation cephalosporin empirically. RESULTS: An Infection occurred in 2 out of 229 cases in group I. One case had an acute superficial infection, which was treated with soft tissue surgery. Another case had delayed deep infection, which occurred 15 months after surgery. There was 1 case of an acute superficial infection out of 197 cases in Group had . There was no infections in the 41 cases in Group III. CONCLUSION: The prophylactic antibiotic effect in group III was similar to those in group I and II. The level of resistance, the number of drug side effects and the economic benefits can be improved by shortening the period of antibiotics use.
