An Isolated Relapse of Acute Lymphoblastic Leukemia as a Chest Wall Mass.
- Author:
Jee Yeon LEE
1
;
Dae Jin SONG
;
Chan Ook WOO
;
Jung Hwa LEE
;
Kwang Chul LEE
Author Information
1. Department of Pediatrics, Korea University College of Medicine, Seoul, Korea. yh951637@chol.com
- Publication Type:Case Report
- Keywords:
Extramedullary relapse;
Acute lymphoblastic leukemia
- MeSH:
Bone Marrow;
Central Nervous System;
Cerebrospinal Fluid;
Child;
Diagnosis;
Drug Therapy;
Etoposide;
Female;
Humans;
Ifosfamide;
Pleural Effusion;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*;
Recurrence*;
Testis;
Thoracic Wall*;
Thorax*
- From:Korean Journal of Pediatric Hematology-Oncology
2002;9(1):117-121
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extramedullary relapse of childhood acute lymphoblastic leukemia (ALL) occurs most commonly in the central nervous system or in the testes. Isolated relapse on chest wall as a soft tissue mass is extremely rare in children with ALL. We experenced a 12-year-old girl who developed an isolated relapse on chest wall during the treatment for ALL. She had a pain and protruding mass on right anterior chest wall 6 months after the initial diagnosis of ALL. Imaging study revealed an 5 7 cm sized soft tissue mass on the right chest wall. Histopathologic examination revealed infiltrates composed of immature lymphoblasts with morphology identical with that of previous bone marrow aspiration. Studies on bone marrow and cerebrospinal fluid were negative for disease at this time. The patient was treated with 3,000 cGy of local irradiation in 10 fractions and systemic chemotherapy with ifosfamide and etoposide. The mass size decreased markedly, but she has been suffering from development of multiple mass in other site and recurrent pleural effusion.
