A Case of Polymorphous Low Grade Adenocarcinoma in Submandibular Gland.
10.3342/kjorl-hns.2014.57.11.778
- Author:
Hun Po CHO
1
;
Young Min LEE
;
Jun Ki LEE
;
Jun Ho PARK
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Daegu Fatima Hospital, Daegu, Korea. jhpark@fatima.or.kr
- Publication Type:Case Report
- Keywords:
Adenocarcinoma;
Salivary gland neoplasm;
Submandibular gland
- MeSH:
Adenocarcinoma*;
Carcinoma, Adenoid Cystic;
Diagnosis;
Diagnosis, Differential;
Follow-Up Studies;
Immunohistochemistry;
Palate;
Recurrence;
Salivary Gland Neoplasms;
Salivary Glands;
Salivary Glands, Minor;
Submandibular Gland*
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2014;57(11):778-782
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polymorphous low-grade adenocarcinoma (PLGA) is a distinctive salivary gland neoplasm with a propensity to arise from minor salivary glands, particularly of the palate. Reports of PLGA have increased with the establishment of specific histopathological criteria characterizing the PLGA, but there are only a few reports of major salivary gland origin. PLGA shares histological features with adenoid cystic carcinoma, so histopathologic diagnosis is essential and immunohistochemistry is an important tool when making differential diagnosis. The treatment of choice is wide surgical excision, and long-term follow up is necessary to evaluate local recurrences. We herein report a case of PLGA arising in a submandibular gland with a review of the relevant literature.