Effects of Burn Injury on the Physis of the Proximal Tibia in the Growing Rat.
- Author:
Guen Chang HO
;
Dong Chang JUN
;
Chang Ju LEE
;
Won Ho CHO
;
Jin Hee SOHN
;
Sang Soo LEE
;
Soo Won JUNG
- Publication Type:Original Article
- Keywords:
Epiphyseal plate;
Proximal tibia;
Thermal injury
- MeSH:
Anesthesia, General;
Animals;
Burns*;
Cell Count;
Ether;
Follow-Up Studies;
Growth Plate;
Inhalation;
Knee;
Leg;
Rats*;
Thigh;
Tibia*
- From:The Journal of the Korean Orthopaedic Association
1997;32(5):1354-1363
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was designed to investigate the effects of burn injury of the leg on the growth plate of proximal tibia in the immature rat. The procedure for burn injury of left leg was performed at the thigh, knee and lower leg under the general anesthesia with inhalation of ether. After the burn injury, follow up observations were made at second day, 1st, 4th, and 6th weeks with histological examination. The results were as follows. During postburn 4 weeks, height of the proximal tibial epiphyseal plates of the experimental group showed significant increment, comparing with control group. At postburn 6th weeks, it revealed no significant difference, comparing with control group (Wilcoxon rank sum test, p<0.05). During postburn 4 weeks, cell numbers in column of the proximal tibial epiphyseal plates of the experimental group showed significant increment, c omparing with control group. At postburn 6th weeks, it revealed no significant difference comparing with control group (Wilcoxon rank sum test, p<0.05).