Experimental study on hemoregulation effects of cracetin
- Author:
Vu Manh Hung
- Publication Type:Journal Article
- Keywords:
Hemoregulation
- MeSH:
Blood;
Animal Experimentation
- From:Journal of Practical Medicine
2005;530(11):39-42
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Method of dissemination intravascular coagulation (DIC) was used on experimental rabbits by intravenous thrombin solution 15 IU. Then rabbits were divided into 3 groups: the control group (8 rabbits) received NaCI 0.9% solution 2 ml/kg W.b/24h; the study group (10 rabbits) received mixed pollution cracetin 10.5 mg/kg/24h; the compare drug group (10 rabbits) received Tanakan solution 4.8 mg/kg w.b. All 3 rabbits groups were orally received in one continuous week. On experimental model of DIC at the dose of 10.5 mg/kg W.b/24h orally within 7 days, cracetin elongated the values of the Howell time, Quick time, thrombin time, partial thrombin time. The drug cracetin increased amount of fibrinogen, restored the number of thrombosis that were consumed more in the progress of forming blood coagulation before.
