Evaluation of Lymph Nodes in Patients with Concurrent Papillary Thyroid Carcinoma and Cervical Tuberculous Lymphadenitis.
10.3342/kjorl-hns.2012.55.9.571
- Author:
Eun Wook CHUNG
1
;
Young Soo CHANG
;
Jungbok LEE
;
Sung Yong CHOI
;
Nak Joon LEE
;
Yoon Kyoung SO
;
Han Sin JEONG
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. hansin.jeong@gmail.com
- Publication Type:Original Article
- Keywords:
Lymph nodes;
Lymphatic metastasis;
Thyroid carcinoma;
Tuberculous lymphadenitis
- MeSH:
Carcinoma;
Humans;
Lymph Nodes;
Lymphatic Metastasis;
Neck;
Neoplasm Metastasis;
Pathology, Surgical;
Retrospective Studies;
Stress, Psychological;
Thyroid Gland;
Thyroid Neoplasms;
Tuberculosis;
Tuberculosis, Lymph Node;
Tuberculosis, Pulmonary;
Tumor Burden
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2012;55(9):571-577
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: To determine the diagnostic clues to differentiate tuberculous lymph node infection from nodal metastasis in patients with both papillary thyroid carcinoma and cervical tuberculous lymphadenitis. SUBJECTS AND METHOD: We retrospectively reviewed 11 patients suffering concurrently from papillary thyroid carcinomas with cervical tuberculous lymphadenitis. Nine of the 11 patients underwent preoperative neck ultrasonography (US) and seven CT scans. Using the surgical pathology as the reference standards, the results of the preoperative diagnostic tools were re-evaluated according to lymph node level-based analysis. US and CT features were also compared between metastatic nodes and tuberculous lymphadenitis. RESULTS: Preoperative CT could localize the involved lymph node levels and differentiate tuberculous infection from metastasis of thyroid carcinoma in only two of seven patients. The site of the involved lymph nodes, the presence of pulmonary tuberculosis, and the tumor volume of the thyroid carcinoma were the clues to diagnose the lymph node status. However, in five of seven cases, CT could not differentiate tuberculosis from metastasis in the lymph nodes. The morphological characteristics of lymph nodes seen on CT and US did not differ between tuberculous infection and metastasis of papillary thyroid carcinomas. CONCLUSION: Pre-operative CT or US does not provide differential information about lymph node status between tuberculous infection and metastasis in patients with concurrent papillary thyroid carcinomas and cervical tuberculous lymphadenitis. Rather, clinical characteristics such as the site of the involved lymph nodes, the primary tumor burden, and the associated clinical features can help the physician differentiate between them.
