Comparative Study of Preoperative Imaging Detection and Localization Test for Hyperparathyroidism.
10.3342/kjorl-hns.2012.55.9.565
- Author:
Eui Suk SUNG
1
;
Yong Bae JI
;
Yun Young CHOI
;
Ji Young KIM
;
Jeong Seon PARK
;
Young Jun LEE
;
Kyung TAE
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Korea. kytae@hanyang.ac.kr
- Publication Type:Comparative Study ; Original Article
- Keywords:
Hyperparathyroidism;
Localization;
Parathyroidectomy;
Ultrasonography;
99mTc-sestamibi scan
- MeSH:
Humans;
Hyperparathyroidism;
Parathyroid Glands;
Parathyroidectomy;
Retrospective Studies;
Technetium Tc 99m Sestamibi
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2012;55(9):565-570
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Accurate preoperative localization of abnormal parathyroid gland is essential for successful parathyroidectomy. The aim of this study was to evaluate the accuracy of a localization test for hyperparathyroidism including ultrasonography (US), computed tomography (CT) and 99mTc-sestamibi scan. SUBJECTS AND METHOD: We studied 47 patients with hyperparathyroidism who underwent parathyroidectomy from January 2003 through December 2010, retrospectively. 99mTc-sestamibi scan, US and CT were carried out as a preoperative localization test and their accuracy were analyzed according to the size, location and pathology of parathyroid lesions. RESULTS: The accuracy of 99mTc-sestamibi scan, US and CT were 93%, 77% and 65%, respectively. The accuracy of 99mTc-sestamibi scan and CT combined was 94% and US and CT 73%. The accuracy of combination of US and 99mTc-sestamibi scan was 96%, which was not different depending on size, location and pathology of parathyroid lesions. CONCLUSION: The combination of 99mTc-sestamibi scan and US is the most effective method for preoperative detection and the localization of hyperparathyroidism.
