The relation between the morphological multiple of FC?RIIA and systemic lupus erythematosus
- Author:
Pham Dang Khoa
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus
- MeSH:
Lupus Erythematosus, Systemic;
Diagnosis
- From:Journal of Practical Medicine
2005;530(11):38-39
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Study on 99 patients with systemic lupus erythematosus (SLE) who were diagnosed and treated at Dermatology hospital, and all patients had surveyed genotype of FC gamma RIIA. The control group consisted of 93 voluntary blood donors who were surveyed genotype of FCRIIA. Genotype of FCRIIA was defined by PCR-SSP method. Results: 4 PCR reactions were used to determine genotype of FCRIIA. The frequency of R/R131, R/H131 and H/H131 in 99 patients occurred in 15 (15.1%), 74 (74.1%) and 10 (10.1%), respectively and in 93 control persons were 11 (11.8%), 50 (53.8%) and 32 (34.4%), respectively. The distribution of frequency of 3 genotype between 2 groups was different with 2 = 16.16 and p<0.01. Genotype of FCRIIA could be the risk factors for the appearance of SLE in Vietnamese people.
