Microbiologic Study of Chronic Sinusitis in Children.
- Author:
Young Chul CHOI
1
;
Tae Chul KIM
;
Eun Ju JEON
;
Yong Soo PARK
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Chronic paranasal sinusitis;
Microbiology;
Polymerase chain reaction
- MeSH:
Acute Disease;
Anti-Bacterial Agents;
Child*;
Coagulase;
Diagnosis;
Drug Resistance, Microbial;
Emergencies;
Haemophilus influenzae;
Humans;
Moraxella (Branhamella) catarrhalis;
Polymerase Chain Reaction;
Prospective Studies;
Respiratory Tract Infections;
Sinusitis*;
Staphylococcus;
Staphylococcus aureus;
Streptococcus;
Streptococcus pneumoniae;
Superinfection
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2000;43(4):391-395
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: The microbiology of chronic sinusitis in children can be anticipated according to the patient's age, clinical presentation, and immunologic state. In acute stage, viral upper respiratory infections frequently precede bacterial superinfection by Streptococcus pneumoniae, Hemophilus influenzae, and Moraxella catarrhalis. In contrast to acute sinusitis, alpha-hemolytic Streptococcus, coagulase negative Staphylococcus and Staphylococcus aureus are common in chronic sinusitis, which may be caused by exacerbations of infection with the bacterial species that cause acute disease. The use of empiric antibiotics directed at the most offending organism is usually appropriate and effective in clinical situation. But the emergency and increasing occurrence of antibiotic resistance has increased the failure rate. MATERIAL AND METHODS: In this prospective study, 50 patients with the diagnosis of chronic sinusitis were evaluated microbiologically by Sinoject (Atos, Sweden) guided aspiration. RESULTS: We cultured alpha-hemoltic Streptococcus in 14 patients, coagulase negative Staphylococcus in 4 patients, Staphylococcus aureus in three patients, gram-positive bacilli in two patients, Streptococcus pneumoniae in one patient. The results of PCR for Hemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis were 32%, 20%, 10%, respectively, and it showed higher detection rates than conventional culture test. CONCLUSION: We advise that all bacterial isolates of cultures of chronic sinusitis in children should undergo appropriate typing and antibiotic sensitivity tests so that the appropriate antibiotic treatment may be employed.
