ABO*Ael03/O Genotype with ABO Discrepancy: The First Case in Korea.
10.3343/alm.2015.35.1.137
- Author:
Bo Kyeung JUNG
1
;
Gye Ryung CHOI
;
Jung Hee CHANG
;
Hye Nan CHO
;
Jong Jin HYUN
;
Myung Hyun NAM
;
Chaeseung LIM
;
Ji Seon CHOI
Author Information
1. Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Korea. salamat@hanmail.net
- Publication Type:Case Reports
- Keywords:
Ael;
Ael03;
ABO subgroup
- MeSH:
ABO Blood-Group System/*genetics;
Alleles;
Base Sequence;
DNA Mutational Analysis;
Exons;
Frameshift Mutation;
Humans;
Male;
Middle Aged;
Pedigree;
Phenotype;
Polymerase Chain Reaction;
Republic of Korea
- From:Annals of Laboratory Medicine
2015;35(1):137-140
- CountryRepublic of Korea
- Language:English
-
Abstract:
The Ael subgroup expresses the least amount of A antigens and could only be detected by performing the adsorption-elution test. The frequency of the Ael subgroup is about 0.001% in Koreans, and the Ael02 allele, which originates from A102, is the most frequently identified allele in the Korean population. We report a Korean family with the Ael03 allele identified by molecular genetic analysis. To the best of our knowledge, this is the first such report in Korea to date.
