A Case of Metachronous Human Papilloma Virus-Associated Squamous Cell Carcinomas in Head and Neck.
10.3342/kjorl-hns.2016.59.3.233
- Author:
Byung Kil KIM
1
;
Gil Joon LEE
;
Bo Young KIM
;
Man Ki CHUNG
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. chungmk@skku.edu
- Publication Type:Case Report
- Keywords:
Cancer of unknown primary;
Human papillomavirus;
Metachronous cancer;
Surgery;
Tonsil cancer
- MeSH:
Carcinoma, Squamous Cell*;
Follow-Up Studies;
Head and Neck Neoplasms;
Head*;
Humans*;
Lymphatic Diseases;
Neck*;
Papilloma*;
Prognosis;
Smoke;
Smoking;
Tonsillar Neoplasms
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2016;59(3):233-237
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck cancers in a Human papillomavirus (HPV)-positive patient without a history of smoking, initially presenting with as a cancer of unknown primary (CUP), and then with a contralateral tonsil cancer with metastatic lymphadenopathy five years later. This report highlights the clinical usefulness of HPV typing to determine the optimal extent of surgery and the follow-up strategy in CUP.
