Antibacteral effect of six Chinese traditional medicines on Yersinia pestis
- VernacularTitle:6种抗菌中药对鼠疫菌抑菌作用观察
- Author:
Jian-jiang, XUE
;
Li-hong, LI
;
Hai-xia, QIAO
;
Jin-jun, LIU
;
Jian-jun, JI
;
Yu-tuo, ZHANG
;
Rui-fu, YANG
;
Jing-fu, QIU
- Publication Type:Journal Article
- Keywords:
Yersinia pestis;
Microbial sensitivity tests;
Anti-bacterial agents
- From:Chinese Journal of Endemiology
2008;27(2):152-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To screen the antibacterial activity of Chinese traditional medicines against Yersinia pestis.Methods Six Chinese traditional medicines(Coptis Chinesis etc)were selected and extracted with pure water to make a concentration of 1 mg/L.Yersinia pestis strain 201 and EV 76 were used to determine the minimal inhibitory concentrations(MIC)of these selected medicines in vitro with liquid dilution method.Results Three herbs had inhibition effects on the strain 201 and EV76 in different extents,among which Rheum palmatum had the strongest effect and MIC was 0.025 00 mg/L.Furthermore,the Chinese traditional medicine had the same MIC on both strain 201 and EV76.Conclusions Chinese traditional medicines commonly used have inhibiting effect on Yersinia pesti.
