Differentiation of malignant from benign pancreatic mass by Tl-201 abdominal SPECT.
10.3346/jkms.1995.10.2.93
- Author:
Hee Seung BOM
1
;
Ho Chun SONG
;
Ji Yeul KIM
;
Sung Kyu CHOI
;
Jong Sun REW
;
Chong Mann YOON
Author Information
1. Department of Nuclear Medicine, Chonnam University Medical School, Kwangju, Korea.
- Publication Type:Original Article ; Clinical Trial ; Research Support, Non-U.S. Gov't
- MeSH:
Abdomen/*radionuclide imaging;
Chronic Disease;
Diagnosis, Differential;
Evaluation Studies;
Female;
Follow-Up Studies;
Human;
Male;
Middle Age;
Pancreatic Neoplasms/*radionuclide imaging;
Pancreatitis/*radionuclide imaging;
Prospective Studies;
Reproducibility of Results;
Sensitivity and Specificity;
Support, Non-U.S. Gov't;
Thallium Radioisotopes/*diagnostic use;
Tomography, Emission-Computed, Single-Photon/methods
- From:Journal of Korean Medical Science
1995;10(2):93-96
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of the present study was to evaluate the ability of Tl-201 abdominal SPECT to differentiate between chronic focal pancreatitis and pancreatic malignancy. Seventeen patients (12 men, 5 women; mean age, 56 years; 9 pancreatic cancer, 8 chronic pancreatitis) with pancreatic mass were prospectively investigated with Tl-201 abdominal SPECT. In all patients, CT and/or US could not clarify the nature of the pancreatic mass. Focal hot uptake was present in 8 of 9 patients with pancreatic cancer, while it was present in 2 of 8 patients with chronic pancreatitis. Therefore, the sensitivity and specificity of the present study were 89% and 75%, respectively. A significant difference of Tl-201 uptakes was noted between benign and malignant masses (p& 0.05). Therefore, we concluded that Tl-201 abdominal SPECT was a useful test in differentiation of malignant from benign pancreatic mass, especially when the differentiation could not be made by other imaging modalities
