Observation on change of lipidemia and lipoprotein in wistar rats wi th fluorosis
- VernacularTitle:慢性氟中毒大鼠血脂及载脂蛋白的变化
- Author:
Kai-yan, LIN
;
Ju-ju, TANG
;
Chong-zhong, BAO
- Publication Type:Journal Article
- From:Chinese Journal of Endemiology
2001;20(2):111-112
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of lipidemia and lipoprotein in wistar rats with fluorosis.Methods 14 wistar rats were fed normal food with hyper concentration of NaF water (100 mg/L) for six months,the TC,TG,HDL-c,LDL-c,APO AI APO B and AI,R-CHE were measured in serum.Results The result show that there are an increace of T C,TG,HDL-c,LDL-c,APO AI，APO B and AI,R-CHD compared with normal rats (P <0.05).Conclusions The result indicate that the fluorosis can increase the lipidemia and lipoprotein in rats with fluorosis and lead to athero selerosis.
