Clinical value of SPECT/CT in differentiating spinal diseases
10.3760/cma.j.issn.0253-9780.2011.04.003
- VernacularTitle:SPECT/CT对脊柱病变鉴别诊断的价值
- Author:
Yong, JIANG
;
Lan, MI
;
Da-fu, YU
;
Xue-xian, DONG
- Publication Type:Journal Article
- Keywords:
Spinal diseases;
Neoplasm metastasis;
Tomography,emission-computed,single-photon;
Tomography,X-ray computed;
MDP
- From:Chinese Journal of Nuclear Medicine
2011;31(4):223-226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of SPECT/CT in differentiating malignancy from benign spinal disease. Methods Fifty-three patients with foci of abnormally increased uptake in the spine detected by 99Tcm-MDP planar whole body bone scan subsequently underwent bone SPECT/CT. The final diagnosis was determined by pathological examination or clinical follow-up ( ≥6 months), which was applied to calculate the diagnostic efficacy of bone SPECT/CT. Results A total of 25 patients were confirmed to have bone malignancy. The diagnostic sensitivity, specificity, accuracy, false positive rate, false negative rate, positive predictive value and negative predictive value for 99Tcm-MDP bone SPECT/CT were 96.00% (24/25), 96.43% (27/28), 96.23% (51/53), 3.57% ( 1/28), 4.00% ( 1/25), 96.00% (24/25) and 96.43% (27/28), respectively. Conclusion 99Tcm-MDP bone SPECT/CT imaging provides good clinical value for the differential diagnosis of spinal diseases.
