Comparison of 99Tcm-MIBI myocardial perfusion imaging and delayed enhancement MRI for patients with idiopathic dilated cardiomyopathy
10.3760/cma.j.issn.0253-9780.2011.04.010
- VernacularTitle:原发性扩张型心肌病心肌灌注显像与心脏磁共振延迟增强成像的对比研究
- Author:
Zhi-xin, JIANG
;
Wei, FANG
;
Chao-wu, YAN
;
Shi-hua, ZHAO
;
Jian, ZHANG
;
Zuo-xiang, HE
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy,congestive;
Tomography,emission-computed,single-photon;
Magnetic resonance imaging;
MIBI
- From:Chinese Journal of Nuclear Medicine
2011;31(4):245-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare 99Tcm-MIBI MPI with delayed enhancement MRI (DE-MRI) in patients with idiopathic dilated cardiomyopathy (IDCM). Methods Forty patients with IDCM were included. They underwent both rest 99Tcm-MIBI myocardial perfusion imaging and DE-MRI within 7 days. 99Tcm-MIBI MPI was performed to identify diffuse or segmental abnormal perfusion patterns including reduced or defect perfusion segments. DE-MRI images were divided into 4 categories: no delayed enhancement, septal, subendocardial and transmural delayed enhancement, x2 test was used for data analysis. Results Diffuse and segmental perfusion abnormality on 99Tcm-MIBI MPI were found in 19 (47.5%) and 21 (52.5%)patients respectively, while DE-MRI enhancement was simultaneously found in 5 patients of the former (5/19, 26.3%) and 18 (18/21, 85.7%) of the latter (x2 =14.401, P<0. 001). For those (n=18) with both segmental perfusion abnormality and DE-MRI enhancement, the number of segments of the 4 DE-MRI respectively. A significant difference was found in the DE-MRI enhancement categories between normal and defect perfusion segments (x2 = 29. 183, P <0.001 ) and between reduced and defect perfusion segments as well (x2 =25. 110, P<0. 001). Conclusions Both diffuse and segmental perfusion abnormalities on 99Tcm-MIBI MPI can be found in patients with IDCM. DE-MRI enhancement is more frequently found in patients with segmental perfusion abnormality.