A Case of Rapidly Progressive Glomerulonephritis (RPGN) Occurring Four Years after Kidney Transplantation.
- Author:
Young Deok BAE
1
;
Soo Jin KIM
;
Teck Man NAM
;
Han Su CHO
;
Seung Hyuk RHO
;
Duck Hyoung YOON
;
Jong Woo YOON
;
Kook Hwan OH
;
Dong Wan CHAE
Author Information
1. Department of Internal Medicine, College of Medicine, Hallym University, Seoul, Korea. cdw1302@hallym.or.kr
- Publication Type:Case Report
- Keywords:
RPGN (rapid progressive glomerulonephritis);
MPGN;
Renal allograft;
Cyclophosphamide
- MeSH:
Adult;
Allografts;
Biopsy;
Cyclophosphamide;
Female;
Glomerulonephritis*;
Glomerulonephritis, Membranoproliferative;
Humans;
Kidney Transplantation*;
Kidney*;
Proteinuria;
Transplants
- From:Korean Journal of Nephrology
2002;21(6):1032-1036
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Immunosuppressive medications after renal allograft transplantation have impacted the course of acute and chronic rejection: however, they have no defined effects on the prevention of recurrent and Glomerulonephritis (GN) in an allograft kidney. Authors experienced a case of rapidly progressive glomerulonephritis (RPGN). The 35-year-old female patient developed a rapid deterioration of renal function 4 years after renal transplantation. The allograft biopsy showed crescentic glomerulonephritis evolving from membranoproliferative glomerulonephritis (MPGN) type I. She was given pulse steroid and oral cyclophosphamide therapy immediately after the renal biopsy. Graft function stabilized and proteinuria decreased even though graft function did not recover to pre-treatment level and low grade proteinuria persisted.
