Risk factors analysis of hyperthyroidism complicated hyperthyroid heart disease
10.3760/cma.j.issn.1000-4955.2011.02.030
- VernacularTitle:甲状腺功能亢进性心脏病危险因素分析
- Author:
Guan-feng, CHONG
;
Jie, GAO
;
Yu-qin, MA
;
Hua-ju, LIANG
;
Xia, ZHANG
;
Xiao-hong, LUO
;
You-zhang, XIANG
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism;
Heart diseases;
Risk factor
- From:Chinese Journal of Endemiology
2011;30(2):211-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the risk factors of hyperthyroid heart diseases(HHD) by analyzing clinical features of patients in order to provide a scientific basis for prevention and treatment of HHD. Methods Nine hundred and eighty two cases were selected as objective from in-patient data of Thyroid Disease Treatment Centre of Shandong Province. The cases were divided into hyperthyroidism group and HHD group. The variables of etiology,sex, age, duration of disease, TSH, FT3, FT4 and TRAb were analyzed by comparative analysis. The risk factors were analyzed by logistic regression. Results The prevalence of hyperthyroidism complicated hyperthyroid heart disease was 7.7%(76/982), age, duration of diseases, FT3, TRAb in the HHD group were [(51.4 ± 11.5), (6.3 ±2.1) years, 21.6 pmol/L, 71.6 U/L], in hyperthyroidism group were [(37.9 ± 9.8), (2.6 ± 1.3) years, 14.9pmol/L, 49.6 U/L]. The differences were statistically significant(u = 9.93,15.23, T = 44954,48792.5, P ＜ 0.05)between the two groups. The factors of the older, higher FT3 and TRAb, longer duration, Graves disease (OR =1.751,1.470,1.483,1.445,1.234) increased the risk of HHD. Conclusions Graves disease, longer duration, old age, higher FT3 and TRAb are the risk factors of HHD. Timely prevention and control of risk factors is necessary to reduce the incidence of HHD.
