Clinical impact of 18F-FDG PET/CT on suspected cervical cancer recurrence
10.3760/cma.j.issn.0253-9780.2011.02.001
- VernacularTitle:18F-FDG PET/CT对可疑复发性宫颈癌的临床价值
- Author:
Ying-ying, HU
;
Xu, ZHANG
;
Wei, FAN
;
Xiao-ping, LIN
;
Pei-yan, LIANG
;
Xin-ru, SUN
- Publication Type:Journal Article
- Keywords:
Cervix neoplasms;
Neoplasm recurrence,local;
Tomography,emission-computed;
Tomography,X-ray computed;
Deoxyglucose
- From:Chinese Journal of Nuclear Medicine
2011;31(2):73-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical impact of 18F-FDG PET/CT on patients with suspected cervical cancer recurrence. Methods Fifty-one cervical cancer patients, clinically suspected to have tumor recurrence during follow-up, underwent 18F-FDG PET/CT examination. 18 F-FDG PET/CT results were compared with those of conventional images, as referred to histopathology or clinical follow-up. Impacts of 18F-FDG PET/CT were evaluated based on documented changes of clinical management. Results In total, 43 patients were found to have positive lesions by 18F-FDG PET/CT, in which 40 were true recurrence,but 2 were pelvic abscess and 1 was radiation enterocolitis. Other 8 patients were found negative by 18F-FDG PET/CT and confirmed by pathology or follow-up. In patient-based analyses, the sensitivity, specificity, and accuracy of 18F-FDG PET/CT for the detection of tumor recurrence were 100% (40/40), 72. 73% (8/11),and 94.12% (48/51) respectively. In 7 patients, the clinical management was changed due to 18F-FDG PET/CT findings. Conclusion 18F-FDG PET/CT is an efficient tool for determining the recurrence of cervical cancer and instructing the clinical management.
