The semiquantitative three-phase bone scintigraphy on hemiplegic patients with earlier complex regional pain syndrome
10.3760/cma.j.issn.0253-9780.2010.04.006
- VernacularTitle:卒中偏瘫早期复杂性区域性疼痛综合征患者的三相骨扫描半定量研究
- Author:
Fang, LI
;
Xing-dang, LIU
;
Zhi-hui, LU
;
Cong-jin, LIU
- Publication Type:Journal Article
- Keywords:
Cerebrovascular disorders;
Hemiplegia;
Complex regional pain syndromes;
Radionuclide imaging;
Skeleton;
MDP
- From:Chinese Journal of Nuclear Medicine
2010;30(4):242-245
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the difference between the early phases and delay phase of three-phase bone scintigraphy on hemiplegic patients with earlier complex regional pain syndrome (CRPS).Methods Twenty-nine stroke patients with hemiplegia complicating CRPS received three-phase bone scintigraphy after intravenous injection of 99Tcm-methylene diphosphonate (MDP). The region of interest (ROI)technique was used to obtain the radioactive counts of involved joints and contralateral sites on wrists,metacarpophalangeal,proximal interphalangeal and distal interphalangeal joints. The total counts of these four sites in each patient were then obtained and the total uptake ratios of involved joints/contralateral joints for each phase were calculated to compare the difference among the three phases. Wilcoxon test and ANOVA were used in data analyses. Results The involved joints of hemiplegic side displayed higher tracer uptake.There were significant differences of the radioactive counts between involved joints and uninvolved ones in the perfusion,pool and delay phase (Wilcoxon test,Z:-4.73 to -2.10,P<0.05). There was no significant difference of total uptake ratios of involved joints/contralateral joints among the three phases ( ANOVA,F = 0. 807,P > 0.05 ). Conclusions Due to higher bone seeking agent accumulation on three-phase bone scintigraphy,both early phases and delay phase imaging showed similar value in stroke patients with hemiplegia complicating earlier CRPS.