The postprandial lipemia,oxidative susceptibility of LDL in patients with coronary heart disease
- VernacularTitle:冠心病患者餐后血脂、LDL氧化活性的变化
- Author:
Honglin, CAI
;
Hui, ZHANG
;
Santan, LI
- Publication Type:Journal Article
- From:
Chinese Journal of Clinical Nutrition
2001;9(1):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the postprandial lipid metabolism in patients with coronary heart disease. Methods 11 CHD cases as CHD group and 15 normal as control group were selected to undergo oral fat load test. Blood samples were obtained before test and 2，4,6 and 8 hours after test. Serum TG, TC, LDL-C,HDL-C, LPO and LDL-LPO-C were calculated. Results 1.Preprandial TG, LDL-C, LPO and LDL-LPO-C in CHD group were significantly higher than that of control group. 2. Postprandial TG, LPO, LDL-LPO-C in CHD group were significantly higher than that of control group. Postprandial HDL-C in CHD group were significantly lower than control group. 3. Postprandial TG (8h), LDL-LPO-C in CHD group were significantly higher than in the preprandial. Postprandial LDL-LPO-C in control group was significantly higher than preprandial. Conclusions 1. Postprandial high-lipemia and dyslipemia was obvious in CHD group. 2. Postprandial high-lipemia was closely related to the development of CHD. 3. Postprandial LDL-LPO-C in CHD group increased significantly and LDL-C sensitivity to oxidative intensified with postprandial time. 4. Postprandial LPO in CHD group increased significantly.
