Research progress in the role of heterogeneous nuclear ribonucleoprotein in the central nervous system
- VernacularTitle:不均一性核糖核蛋白(hnRNP)在中枢神经系统中的作用
- Author:
Yi-chen, LIU
;
Chang-hong, REN
;
Hang-yan, WANG
;
Cheng-gang, ZHANG
- Publication Type:Journal Article
- Keywords:
heterogeneous nuclear ribonucleoprotein;
neuron;
glial cell;
central nervous system;
nervous system disease
- From:Bulletin of The Academy of Military Medical Sciences
2010;34(1):80-83
- CountryChina
- Language:Chinese
-
Abstract:
Heterogeneous nuclear ribonulcleoprotein(hnRNP)plays a variety of roles in pre-mRNA splicing, nuclear export of mRNA and turnover. It is reported that hnRNP not only takes part in regulating the development of neuron and glial cells, but is closely related to various central nervous system diseases. This paper reviewed the structure, function and the role of hnRNP in the central nervous system in order to provide new insight into the molecule mechanism of nervous system diseases.
