Study on prediction of CTL Epitope for Yersinia pestis antigens
- VernacularTitle:鼠疫菌抗原CTL表位预测方法的建立
- Author:
Wen-jing, WANG
;
Yan-ling, ZHANG
;
Ming, LI
- Publication Type:Journal Article
- Keywords:
CTL epitope;
Forecasting;
LcrV;
,antigens
- From:Chinese Journal of Endemiology
2008;27(6):683-685
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method predicting CTL epitopes of antigens in Yersinia pestis,which provides an effective research plan for epitnmics in Yersinia pestis.Methods CTL epitopes were predicted by nHLAPred.BIMAS and SYFPEITHI.Results CTL epitopes of LcrV antigen were detected as V8-16 NPQHFIEDL,V311-319 KYDSVMQRL and V258-264 SYNKDNNEL.Conclusions Prediction of CTL epitope can be used to make epitope mapping because of its hiigh accuracy.It may provide a reference for the epitope mapping plan.
