Advances in research on liver-specific biologically active peptides
- VernacularTitle:肝特异性生物活性肽研究进展
- Author:
Jing, CHANG
;
Chun-Ping, CUI
;
Chu-ze, WU
- Publication Type:Journal Article
- Keywords:
liver regeneration;
hepatocytes;
cell proliferation;
hepatocyte growth factor;
epidermal growth factor;
HSS;
ALR;
HPS;
HPPCn;
biologically active peptides
- From:Bulletin of The Academy of Military Medical Sciences
2009;33(6):577-579
- CountryChina
- Language:Chinese
-
Abstract:
The liver is an important organ of the body,with an extraordinary capacity for responding to physical or chemical injuries by regenerating. The mechanisms behind liver regeneration are very complicated as hundreds of substances are involved.However,most of them are not liver-specific,such as HGF,EGF etc. We recently isolated a pure protein with hepatic stimulatory activity from the extract of a weanling calf liver and named its hepatopoietin Cn (HPPCn).This paper,with reference to our own work, mainly reviews the development and bioactivity about hepatic stimulator substance(HSS),augmenter of liver regeneration(ALR),hepassocin(HPS) and HPPCn,which are liver-specific biologically active peptides.
