A clinical comparative study of 99Tcm-tetrofosmin with 99Tcm-MIBI in breast carcinoma and axillary lymph node metastases
- VernacularTitle:乳腺癌及腋淋巴结转移99Tcm-tetrofosmin与99Tcm-MIBI显像的对比研究
- Author:
Weikun, HUANG
;
Guoxin, LI
;
Delin, QI
- Publication Type:Journal Article
- From:Chinese Journal of Nuclear Medicine
2001;21(2):95-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical diagnostic value of 99Tcm-tetrofosmin in the imaging of breast carcinoma and axillary lymph node metastases and to compare with that of 99Tcm-MIBI. Methods 52 females with breast masses were examined by 99Tcm-tetrofosmin scintigraphy and 99Tcm-MIBI scintigraphy.All the results were compared with that from pathologic study. Results 26 patients were found to have a primary malignancy of the breast ,whereas 30 had benign disease. 99Tcm-tetrofosmin breast imaging showed abnormal uptake in 21 of 26 malignancies and in 11 of 16 axillary lymph node metastases.The sensitivity ,specificity, and accuracy values obtained with 99Tcm-tetrofosmin and 99Tcm-MIBI scintigraphy for breast carcinoma were 80.8%, 76.7%, 78.6%,and 73.1%,73.3%,73.2%, respectively. The values obtained with 99Tcm-tetrofosmin and 99Tcm-MIBI scintigraphy for axillary lymph node metastases were 68.8%, 80.0%, 76.0%,and 75.0%,80.0%,76.9%, respectively. Conclusions Both of the two techniques are effective in the differentiation of malignant breast mass-es from benign ones and in detecting axillary lymph node metastases.However , 99Tcm-tetrofosmin is superior to 99Tcm-MIBI in detecting breast carcinoma.
