A sero-epidemiologic survey on human plague in source of three rivers area Qinghai from 2005 to 2007
- VernacularTitle:2005-2007年青海省三江源地区人群鼠疫血清流行病学调查报告
- Author:
Yong-hai, YANG
;
Xiu-min, HAN
;
Chao, LI
;
Li, WANG
;
Xiao-long, ZHAO
;
Shou-hong, YU
;
Shao-zhen, WEI
;
Han-qing, YANG
;
Li-xia, JIN
;
Gang, NING
- Publication Type:Journal Article
- Keywords:
Plague;
Serecpideminlogie studies;
Antibodies
- From:Chinese Journal of Endemiology
2008;27(4):441-442
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of human plague using a sero-epidemiologic method in the source of the three rivers area in Qinghai for possible plague control strategies. Methods Investigate human plague sero-epidemiologically in the source of 4 counties in the three rivers area in Qinghai. The human serum would be tested to confirm the sew-positive rate for plague F1 antibody using indirect hemagglutination assay(IHA). Results A total of 2508 local participants were tested in 4 counties, the overall plague sero-positive rate was 2.31%(58/2508). This represents a statistically significant difference with 4 counties(X2=19.30,P<0.01). The sew-positive rate for males and females were 2.54% (32/1261) and 2.09% (26/1247), respectively. There were no statistically significant differences between males and females(X2= 0.65,P 0.05). The sero-positive rate in herdsman, cadre, Tibetan, Hart nationalities were 3.54% (44/1243), 6.47% (11 / 170), 2.40% (56/2335) and 1.47% (2/136), respectively. The sero- positive rate increased with age. The highest titre for human plague serum antibody was 1 : 640. Conclusion There were occult infections of plague in the population on source of three rivers area in Qinghai. Sero-epidemiologic data revealed that the human plague sero-positive rate was closely correlated with the local animal plague.